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Sustained Increase of HDL Cholesterol Over a 72-Week Period in HIV-Infected Patients Exposed to an Antiretroviral Regimen Including Lopinavir/Ritonavir
Jean-Luc Meynard,
Karine Lacombe*,
Jean-Marie Poirier,
Olivier Massot,
Bénédicte Lefebvre,
Olivier Bouchaud,
Jean-Baptiste Guiard-Schmidt,
Alvaro Martinez,
Pascale Benlian,
and
Pierre-Marie Girard
* To whom correspondence should be addressed. E-mail: karine.lacombe{at}sat.aphp.fr.
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Abstract |
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Metabolic disorders are a major concern during antiretroviral therapy, especially for their potential to increase cardiovascular disease risk. In a multi-center, prospective study conducted in patients exposed to an antiretroviral regimen including lopinavir boosted with ritonavir (LPV/r), an early and sustained increase of HDL-cholesterol was observed over a 72- week period. This increase was positively correlated with the exposure to LPV/r during the first 24 weeks.
First published on November 17, 2008, doi:10.1177/1545109708326088
Journal of the International Association of Physicians in AIDS Care (JIAPAC) 2008;7:311.
A more recent version of this article appeared on December 1, 2008

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