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Journal of the International Association of Physicians in AIDS Care (JIAPAC)
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1545109708322015v1
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Article

Impact of Education and Support on the Tolerability and Quality of Life in a Cohort of HIV-1 Infected Patients Treated With Enfuvirtide (SURCOUF Study)

Clotilde Allavena*, Thierry Prazuck, Véroniquer Reliquet, Renaud Verdon, Philippe Perré, Gwenael Le Moal, Eric Billaud, and François Raffi

* To whom correspondence should be addressed. E-mail: clotilde.allavena{at}chu-nantes.fr.


   Abstract
The aim of this study was to evaluate the quality of life and the intensity of the injection site reactions during the first 6 months of treatment with enfuvirtide according to the counseling and training provided by nurses and physicians. In this prospective, 6-month cohort, 61 HIV1 infected adult patients starting enfuvirtide have been included. At baseline, 82% of the patients have either read information documents (23%) or received counseling (59%); 18% were self-injectors, 27.8% had a dual disposition (self-injector + third person), and 49.2% were injected by a third person. At month 6, among the 43 patients still on enfuvirtide, 59% have had no change in injection disposition, and 52% have the dual disposition. Quality of life and enfuvirtide acceptance improved during 6 months. With adequate education and choice of injection dispositions, treatment with enfuvirtide can lead to quality-of-life improvements.

First published on July 3, 2008, doi:10.1177/1545109708322015

Journal of the International Association of Physicians in AIDS Care (JIAPAC) 2008;7:187.

A more recent version of this article appeared on July 1, 2008


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