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Journal of the International Association of Physicians in AIDS Care (JIAPAC)
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1545109708320686v1
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Article

Validity of Self-Reported Adherence Among Injection Drug Users

Thomas Kerr*, Robert S. Hogg, Benita Yip, Mark W. Tyndall, Julio Montaner, and Evan Wood

* To whom correspondence should be addressed. E-mail: uhri{at}cfenet.ubc.ca.


  Abstract
Background: In Vancouver, the availability of prescription refill data for all HIV-infected individuals plus a prospective cohort of injection drug users (IDUs) permitted an examination of the validity of self-reported highly active antiretroviral therapy (HAART) adherence among IDUs. Methods: Self-reported HAART adherence among Vancouver Injection Drug Users Study participants was compared with pharmacy refill rates from the British Columbia Drug Treatment Program database. Pearson’s correlation coefficient and Pearson’s {chi}2 test were used to assess associations between adherence as measured by self-report and pharmacy refill data. Results: Among 88 HIV-infected IDUs, 48 (55%) had an adherence rate of ≥75% as measured by pharmacy refill adherence, whereas 81 (92%) had an adherence rate of ≥75% as measured by self-report. Self-reported adherence was not statistically associated with pharmacy refill adherence (P > .1). Conclusion: These findings suggest that the validity of self-report measures may be limited when applied to community-recruited IDUs.

First published on July 14, 2008, doi:10.1177/1545109708320686

Journal of the International Association of Physicians in AIDS Care (JIAPAC) 2008;7:157.

A more recent version of this article appeared on July 1, 2008

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