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Possible Case of CNS Whipple's Disease in an Adolescent With AIDS
Sameer J. Patel*,
Richard C. Huard,
Christian Keller,
and
Marc Foca
* To whom correspondence should be addressed. E-mail: sp2172{at}columbia.edu.
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Abstract |
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An adolescent with HIV/AIDS presented subacutely with progressive encephalopathy, spastic quadraplegia, and diarrhea. His brain biopsy was suggestive of central nervous system Whipples disease, a disease rarely described in HIV patients. Due to overlapping, nonspecific symptoms associated with several opportunistic infections and to the difficulty in culturing the causative organism Tropheryma whipplei, Whipples disease may be more common than previously suspected, and it is an important consideration in patients with AIDS.
First published on March 4, 2008, doi:10.1177/1545109708315328
Journal of the International Association of Physicians in AIDS Care (JIAPAC) 2008;7:69.
A more recent version of this article appeared on April 1, 2008

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