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Lymphadenopathy—An Important Guiding Tool for Detecting Hidden HIV-Positive Cases: A 6-Year Study

Department of Microbiology, Pt. B. D. Sharma Postgraduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India, pjsgill{at}rediffmail.com

D.R. Arora, MD

Department of Microbiology, Maharaja Agarsen Medical College, Agroha, Haryana, India

B. Arora, MD

Department of Pathology, PGIMS, Rohtak, Haryana, India

Meenu Gill, MD

Department of Pathology, PGIMS, Rohtak, Haryana, India

Vikas Gautam, MD

Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

Jai Karan, MBBS

Department of Microbiology, PGIMS, Rohtak, Haryana, India

Uma Chaudhary, MD

Department of Microbiology, PGIMS, Rohtak, Haryana, India

Nidhi Garg, MD

Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

Lymphadenopathy is one of the leading and persistent signs during the progression of human immunodeficiency virus (HIV) infection. Lymphadenopathy, as a clinical sign, can become one of the important guiding tools for detecting hidden HIV-positive cases. The present study was conducted to assess the incidence of HIV positivity in previously undiagnosed patients of HIV presenting with lymphadenopathy, comparing it with the current trends of HIV infection in the community, and to ascertain the etiology of lymphadenopathy in HIV-positive and HIV-negative cases. Over a period of 6 years, a total of 1082 cases of extra-inguinal lymphadenopathy were screened for HIV infection. Simultaneously, fine needle aspiration cytology of the enlarged lymph nodes was performed to know the etiology. The incidence of HIV positivity was found to be 2.3% among the patients presenting with lymphadenopathy. Among the HIV-positive cases, tuberculous lymphadenopathy was found in 60% of cases as compared to 28% of cases in HIV-negative cases. Alarmingly high incidence of HIV infection among the lymphadenopathy cases has been observed. This necessitates the importance of exercising vigilance, caution, and a high degree of suspicion while dealing with patients of lymphadenopathy, to protect ourselves as well as a much larger population at risk from this scourge.

Key Words: HIV • lymphadenopathy • hidden cases

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This version was published on December 1, 2007

Journal of the International Association of Physicians in AIDS Care (JIAPAC), Vol. 6, No. 4, 269-272 (2007)
DOI: 10.1177/1545109707304298


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This Article Abstract Free Full Text (Free PDF) Free Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Gill, P.S. Articles by Garg, N. Search for Related Content PubMed PubMed Citation Articles by Gill, P.S. Articles by Garg, N. Social Bookmarking                         What's this?