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High Seroprevalence But Low Incidence of HCV Infection in a Cohort of Patients With Sexually Transmitted HIV in Andalusia, Spain

Hospital Virgen de la Victoria, Malaga, med006809{at}saludalia.com

Rosario Mata, MD

Hospital Virgen del Rocío, Sevilla

Isabel Aguilar, MD

Hospital Virgen de la Victoria, Malaga

Leopoldo Muñoz, MD

Hospital San Cecilio, Granada

M. José Ríos, MD

Hospital Virgen Macarena, Sevilla

Salvador Vergara, MD

Hospital Valme, Sevilla

Antonio Rivero, MD, PhD

Hospital Reina Sofía, Córdoba

Dolores Merino, MD

Hospital Juan Ramón Jiménez, Huelva Spain

Luis F. López-Cortés, MD, PhD

Hospital Virgen del Rocío, Sevilla

Alejandro Peña, MD

Hospital San Cecilio, Granada

Jesús Santos, MD PhD

Hospital Virgen de la Victoria, Malaga,

Group for the Study of Viral Hepatitis of SAEI

Purpose. To analyze the prevalence and the incidence of hepatitis C virus (HCV) seropositivity in sexually transmitted human immunodeficiency virus (HIV) patients. Methods. Observational study of 1468 sexually transmitted HIV-infected patients from 7 hospitals (Southern Spain). Characteristics of HCV cases, and incidence of HCV seroconversion was assessed. Results. Seroprevalence of HCV was 16.1%, higher among heterosexual than homosexual patients, and similar between heterosexual men and women. Seroincidence was 0.16 cases per 100 patient-years, similar between homosexual and heterosexual patients. HCV patients had a mean CD4 of 523 cells/µL, 82.0% were on highly active antiretroviral therapy (HAART), and 72.0% had undetectable HIV viral load. Serum HCV-RNA was positive in 79.0% cases, and only 16.0% had ever received HCV treatment. Conclusions. HCV seroprevalence among sexually transmitted HIV-infected patients is more frequent than in the general population; however, incidence of HCV infection is currently low. Patients with sexually transmitted HIV coinfected with HCV have their HIV infection well controlled, but HCV infection was treated in few cases.

Key Words: HCV infection • HIV infection • sexual transmission

This version was published on March 1, 2009

Journal of the International Association of Physicians in AIDS Care (JIAPAC), Vol. 8, No. 2, 100-105 (2009)
DOI: 10.1177/1545109709331474


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