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Journal of the International Association of Physicians in AIDS Care (JIAPAC)
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Lessons Learned From 2 Patients With Multidrug-Resistant HIV-1 Infection Successfully Treated With a Darunavir-Containing Antiretroviral Treatment Regimen

Robert Colebunders, MD, PHD

Institute of Tropical Medicine, Antwerp, Belgium, University Hospital Antwerp, Antwerp, Belgium, bcoleb{at}itg.be

Erika Vlieghe, MD

Institute of Tropical Medicine, Antwerp, Belgium, University Hospital Antwerp, Antwerp, Belgium

Ula Maniewski, MD

Institute of Tropical Medicine, Antwerp, Belgium, University Hospital Antwerp, Antwerp, Belgium

Tom Schepens

University Hospital Antwerp, Antwerp, Belgium

Els Hollanders

Tibotec, a division of Janssen-Cilag, Berchem, Belgium

Eric Gheuens, MD, PHD

Tibotec, a division of Janssen-Cilag, Berchem, Belgium

Ann De Roo, MD

Institute of Tropical Medicine, Antwerp, Belgium

The authors describe 2 patients with life-threatening multidrug-resistant HIV-1 infection who responded very well to a treatment regimen containing darunavir and enfuvirtide. They discuss the availability of several new treatment options such as darunavir, etravirine, integrase, and CCR5 inhibitors for patients with multidrug-resistant viruses.

Key Words: HIV • antiretroviral treatment • darunavir • resistance

This version was published on September 1, 2007

Journal of the International Association of Physicians in AIDS Care (JIAPAC), Vol. 6, No. 3, 203-205 (2007)
DOI: 10.1177/1545109707304122
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