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Journal of the International Association of Physicians in AIDS Care (JIAPAC)
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Pre-Exposure Chemoprophylaxis (PREP) as an HIV Prevention Strategy

Mike Youle, MB, ChB

Royal Free Centre for HIV Medicine, London, UK

Mark A. Wainberg, PhD

McGill University AIDS Centre, Montreal, Canada

Chemoprophylaxis may be a prevention strategy for the sexual transmission of human immunodeficiency virus (HIV). Evidence suggests that condom use has waned with the availability of antiretroviral medication, at least in some resource-rich settings. Barrier methods of HIV prevention have inherent problems, and the potential for failure. Microbicide research has focused primarily on male-to-female transmission. Analogous to post-exposure prophylaxis, HIV prevention may be achieved by pre-exposure prophylaxis in some settings. Research in this potential strategy may be rewarding.

Key Words: HIV • chemoprophylaxis • prevention • antiretroviral

Journal of the International Association of Physicians in AIDS Care (JIAPAC), Vol. 2, No. 3, 102-105 (2003)
DOI: 10.1177/154510970300200302
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Home page
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A. Y. Liu, R. M. Grant, and S. P. Buchbinder
Preexposure prophylaxis for HIV: unproven promise and potential pitfalls.
JAMA, August 16, 2006; 296(7): 863 - 865.
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